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Regenerative and
Transitional Therapy

Yorkville, Toronto

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Science and evidence-based medicine and procedures
for regeneration, remodulation and anti-aging.

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The Future is Here

Regenerative and transitional medicine is a new and revolutionary field of medical diagnostic and treatment. It focuses on repairing and healing tissues in an efficient and safe way.

These methods would’ve taken years and decades to reach patients and communities, but we’re bringing them to you now.

About Us

We are pioneers in Regenerative and Transitional Therapy. Our procedures promote healing, regulate cellular functions, implement immunomodulation and regenerate tissue.

We use a multidisciplinary, collaborative, safe and evidence-based approach to expedite bench-to-bedside delivery of medical advancement.

Our expertise


We use stem cells and other biologics to treat and repair damaged tissues. The advances in biotechnology and cell biology allow us to treat conditions that were deemed untreatable.


We boost the body’s natural healing potential by providing proteins and molecules. They eliminate any toxic and damaging processes in a tissue. It allows us to promote the tissue into a healthy state faster.


We use stem cells and other non-synthetic biologics to naturally restore tissues. We rejuvenate skin, joints and muscles, restore mobility and give them natural purity.


Our cutting edge treatments enrich aging skin with collagen and repair damaged DNA at the cellular level without any side effects.


Chondrostem™ is our proprietary technology; a marrow-based cell therapy allograft that regenerates, heals cartilage, and repairs damaged tissue.

It shuts down inflammation and degeneration as well as restores the natural matrix leading to full recovery and healing.

Start your journey
to a better you

Book a free consultation to talk with a doctor, ask questions about your health and get 5% off your first treatment.

Professional Advice
Personable Approach
No obligations

Book a Free consultation
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Whether you are just starting your research, have questions, or ready to get treated, we are here to help.

or call us +1 416 479 8667

Your Trusted Expert

Dr. Riam Shammaa. MD.CCFP(SEM)

Dr. Shammaa is a national expert in musculoskeletal, regenerative and pain medicine. He serves as the Medical Director at CCRT and the lead scientist at the National Institute for Stem cell Research. He is a pioneer in autologous and allogeneic stem cell treatments.

He was the first to conduct a spinal discs repair using stem cells in Canada. Dr. Shammaa lectures at the University of Toronto and across Canada on Musculoskeletal diseases, stem cells, Translational medicine and regenerative medicine.



Our procedures promote safe and efficient healing, regulate cellular functions, implement immunomodulation and regenerate damaged tissue.

  • Knee and leg Conditions
    • Osteoarthritis of the Knee
    • Chronic Knee Pain
    • Patellar Tendinopathy
    • Patellar Tendon Tears
    • Degenerative Meniscal Tears
    • Non operative Stable Meniscal Tears
    • Partial Thickness Ligamentous Tears (ACL, MCL, LCL, PCL)
    • Adductors Tears and Strains
    • Hamstring Tears and Strains
    • Chronic Peripatellar Bursitis
    • Shin Splints
    • Stress Fractures

  • Hip Conditions
    • Chronic Hip Pain
    • Avascular Necrosis of Femoral Head
    • Osteoarthritis of the Hip
    • Greater Trochanteric Bursitis
    • Gluteus Muscles Tears
    • Hip Flexors Tendinopathies and Tears
    • Sacroiliac Joint Arthritis
    • Sacroiliac Joint Dysfunction

  • Elbow Conditions
    • Arthritis of the Elbow
    • Tennis Elbow (Lateral Epicondylopathy)
    • Golf Elbow (Medial Epicondylopathy)
    • Triceps Tears and Tendinopathies
    • Hand and Wrist Conditions
    • Arthritis of the Wrist
    • Thumb Arthritis (CMC)
    • De Quervain’s Tenosynovitis
    • Arthritis of the finger
    • Stable TFCC Tears

  • Ankle and Foot Conditions
    • Arthritis of the Ankle Joint
    • Achilles TendinopathyAchilles Partial Tears
    • Achilles Partial Tears
    • Calf Muscle Tears (Gastrocnemius and Soleus)
    • Cartilage Loss and Damage of the Ankle
    • Pain from tendon tears or overstretched ligaments and ankle sprains
    • Plantar Fasciitis

  • Shoulder Conditions
    • Rotator Cuff Tendonitis
    • Shoulder Osteorthritis
    • Shoulder Bursitis
    • Rotator Cuff Full and Partial Tears
    • AC joint Arthritis
    • Biceps Tendinosis
    • Biceps Tendon Partial Tears
    • Degenerative Cartilage Tears
    • Stable Labral Tears
    • Pectoralis Major Tears


Unfortunately, osteoarthritis can not be reversed. It’s why after trying medication and therapy, patients often turn to surgery, which isn’t the only option. Our treatments can reduce pain, help you move better, and heal.

  • Joint Pain

    Our procedures allow us to remodulate and regenerate the intra-articular cartilage towards healing without joint replacement with a 92% success rate.

  • Back Pain

    We are the only doctors in Canada that are able to repair mechanical back pain without surgery and substantially alleviate related problems.

  • Conditions treated
    • Osteoarthritis
    • Shoulder arthritis
    • Hip arthritis
    • Knee arthritis
    • Wrist arthritis
    • Ankle arthritis
    • Back arthritis
    • Cartilege Regeneration


We offer treatments to refresh your skin, maintain your appearance and prevent it from aging.

Using stem cell therapy and PRP, we are able to fight aging processes, stimulate the circulation of lymph, accelerate the production of collagen and elastin.

  • Conditions treated
    • Wrinkles and Fine Lines
    • Skin Rejuvenation
    • Hair Loss
    • Improving Skin Quality
    • Dynamic Expression Lines
    • Dark Circles Under the Eyes
    • Sun Damaged Skin
    • Acne Scars
    • Burning Scars
    • Wound Healing
    • Melasma and Pigmentation Breakdown

What Patients Say

Our patient’s most valuable words.
See what they say about us!

150+ Patients Love

  • “I’m thrilled to report that both hips have miraculously returned to normal! No pain, no stiffness, great mobility….Hooray! So, if you agree, I am not going to go ahead with second PRP shots now, but take a wait and see position and hope that the first shots did the trick. My hands are now 70% better after only 4 days. Please advise when the earliest I can come back for the second shoulder shot.”

    Mr. Breslin

  • “I’ve started walking again, and my left knee feels fine, my right knee which was more degenerative, still aches when I’m walking, but not as much or as often as before. Swelling has gone quite a bit, and I’m being patient in regards allowing the treatment to take the time it needs for healing…already I am seeing improvements. Thanks very much for your help.”

    Carmen R.


    • What is Regenerative Therapy?

      Regenerative Therapy is a branch of translational research in tissue engineering and molecular biology which deals with the “process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function.”

    • What is PRP?

      PRP, or Platelet-Rich Plasma, supports faster healing of soft tissue injuries of tendons, ligaments and muscles. It uses the body’s own blood to naturally stimulate tissue and wound healing, and may eliminate the need for more extensive treatment, such as surgery.

    • What are Stem Cells?

      Stem Cells are a regenerative cell-based therapy that can be used for the management of inflammatory conditions such as tendonitis, joint pain associated with early arthritis, and cartilage damage.

      When the body sustains damage from trauma, disease or simple wear and tear, it normally results in the formation of a wound. These wounds can be external or internal to the body, affect a specific tissue or structure, and often result in a void or loss of tissue. As part of the body’s normal healing mechanisms, a biological process begins to repair the damaged area. To help the body’s own healing mechanisms, stem cells can be used.

    • What Conditions are treated by Stem Cell and PRP injections?

      We use stem cell injections to treat inflammatory conditions and joint pain such as:

      • Osteoarthritis (knees and shoulders)
      • Plantar fasciitis
      • Tendonitis
      • Wrist and joint pain
      • Tennis or golf elbow
      • Rotator cuff tears
      • Bursitis
      • Muscle and tendon injuries such as calf and hamstrings

    • What are the Potential Benefits of Stem Cell and PRP Injections?

      Potential Benefits of Stem Cell and PRP Injections are the folowing

      • Potential Benefits of Stem Cell and PRP Injections are the folowing Improve symptoms
      • Regain function after injury
      • Eliminate the need for more aggressive treatments such as long-term medication or surgery


    • The Stem Cells Used in SCT Come from Embryos

      Not true. They actually come from your own body. They are called Adult Stem Cells. Human fat tissue is the largest natural source of stem cells, but when you suffer an injury your body can’t supply enough of these valuable stem cells to the injured area. We use an Adipose Transfer System (ATS) to retrieve these stem cells and re-inject them to the injured area.

    • SCT is “against the law.”

      This myth relates to Myth #1, as the use of “embryonic” stem cells is considered controversial, especially in the U.S. But the use of Adult Stem Cells from your own body is approved by Canadian health agencies, and has even been blessed by religious leaders such as previous Pope Benedict.

    • Your Body Will “Reject” the Cells

      Some people confuse SCT with an organ transplant, in which some donor organs can be rejected. But since these are your body’s own cells being used, there is no chance for rejection.

    • SCT is as Invasive as Surgery

      Nothing could be further from the truth. Patients are only given a local anesthetic, the procedure only takes a few hours in an outpatient setting, and people are generally back to work within a day or two.

      The facts show that regenerative therapies like SCT empower people to live without pain, and take charge of their health.

      It’s time to recover fully, without surgery.

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